Level of Interferon Gamma in the Blood of Tuberculosis Patients
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Abstract:
Background: Interferon gamma (IFN-γ), a cytokine produced by a variety of cells is involved in the immune response against M. tuberculosis. It activates the production of other cytokines and molecules that kill mycobacterium. IFN-γ also has diagnostic role in identification of active and latent tuberculosis. Objective: To determine the level of IFN-γ in the blood of TB patients. Methods: Ninety-one subjects were selected, including 54 active TB patients and 37 healthy controls. Among 54 TB patients, 27 had confirmed TB and 27 were clinically diagnosed as having TB. IFN-γ concentration was determined in their blood by an ELISA technique. Results: In TB patients, Mean + SD of IFN-γ was 48.69 + 28.78 pg/ml while it was 12.99 + 5.70pg/ml in the control group (p
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level of interferon gamma in the blood of tuberculosis patients
background: interferon gamma (ifn-γ), a cytokine produced by a variety of cells is involved in the immune response against m. tuberculosis. it activates the production of other cytokines and molecules that kill mycobacterium. ifn-γ also has diagnostic role in identification of active and latent tuberculosis. objective: to determine the level of ifn-γ in the blood of tb patients. methods: ninety...
full textLevel of interferon gamma in the blood of tuberculosis patients.
BACKGROUND Interferon gamma (IFN-γ), a cytokine produced by a variety of cells is involved in the immune response against M. tuberculosis. It activates the production of other cytokines and molecules that kill mycobacterium. IFN-γ also has diagnostic role in identification of active and latent tuberculosis. OBJECTIVE To determine the level of IFN-γ in the blood of TB patients. METHODS Ninet...
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Journal title
volume 7 issue 4
pages 240- 246
publication date 2010-12-01
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